INJE PharmacoGenomics Research Center

· Gwak J, Park S, Cho M, Song T, Cha SH, Kim DE, Jeon YJ, Shin JG, Oh S.

Polysiphonia japonica extract suppresses the Wnt/beta-catenin pathway in colon cancer cells by activation of NF-kappaB. ()

Int J Mol Med. 2006 Jun;17(6):1005-10. [LINK]

2006-International

· Kim H, Yoon YJ, Kim H, Kang S, Cheon HG, Yoo SE, Shin JG, Liu KH.

Characterization of the cytochrome P450 enzymes involved in the metabolism of a new cardioprotective agent KR-33028. (FRONTIER)

Toxicology Letters, 200606, 166, 105~114 [LINK]

2006-International

· Park S, Gwak J, Cho M, Song T, Won J, Kim DE, Shin JG, Oh S.

Hexachlorophene inhibits Wnt/beta-catenin pathway by promoting Siah-mediated beta-catenin degradation. ()

Mol. Pharmacol, 200605, 70(3) 960-966 [LINK]

2006-International

· Park JY, Kim KA, Park PW, Lee OJ, Kang DK, Shon JH, Liu KH, Shin JG.

Effect of CYP3A5*3 genotype on the pharmacokinetics and pharmacodynamics of alprazolam in healthy subjects. (PRCDM)

Clin Pharmacol Ther 2006;79:590-9 [LINK]

2006-International

· Lee SY, Sohn KM, Ryu JY, Yoon YR, Shin JG, Kim JW.

Sequence-based CYP2D6 genotyping in the Korean population. (PRCDM)

Ther Drug Monit 2006;28:382�387 [LINK]

2006-International

· Kang HJ, Lee SS, Lee CH, Shim JC, Shin HJ, Liu KH, Yoo MA, Shin JG.

Neurotoxic pyridinium metabolites of haloperidol are substrates of human organic cation transporters. (NRL, PRCDM)

DMD 34:1145�1151, 2006 [LINK]

2006-International

· Park JY,Shon JH, Kim KA, Jung HJ, Shim JC, Yoon YR, Cha IJ, and Shin JG

Combined Effects of Itraconazole and CYP2D6*10 Genetic Polymorphism on the Pharmacokinetics and Pharmacodynamics of Haloperidol in Healthy Subjects (PRCDM)

Journal of Clinical Psychopharmacology, Volume 26, Number 2, April 2006 [LINK ]

2006-International

· Kim H, Yoon YJ, Shon JH, Cha IJ, Shin JG, Liu KH.

Inhibitory effects of fruit juices on cyp3a activity. (NRL, PRCDM)

Drug Metab Dispos. 2006 Apr;34(4):521-3. Epub 2006 Jan 13. [LINK]

2006-International

· Liu KH, Kim MJ, Jeon BH, Shon JH, Cha IJ, Cho KH, Lee SS, Shin JG.

Inhibition of human cytochrome P450 isoforms and NADPH-CYP reductase in vitro by 15 herbal medicines, including Epimedii herba. (PRCDM)

J Clin Pharm Ther. 2006 Feb;31(1):83-91. [LINK]

2006-International

· Kim H, Kang S, Kim H, Yoon YJ, Cha EY, Lee HS, Kim JH, Yea SS, Lee SS, Shin JG, Liu KH.

In vitro metabolism of a new cardioprotective agent, KR-32570, in human liver microsomes. (FRONTIER, PRCDM)

Rapid Commun Mass Spectrom. 2006;20(5):837-43. [LINK]

2006-International

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